Spravato® (esketamine) is an FDA-approved nasal spray used in combination with an oral antidepressant to help treat adults with Treatment-Resistant Depression (TRD). Unlike traditional antidepressants—which can take weeks to work and often target serotonin—Spravato works differently by acting on the brain’s NMDA receptors. This unique mechanism helps restore synaptic connections that may have been damaged by long-term depression and stress, often leading to faster symptom relief.

Administered in a secure, comfortable clinical setting at La Mente Behavioral Health, Spravato is given under the supervision of trained medical professionals to ensure your safety throughout each treatment session. Most patients begin to experience improvements in mood, emotional clarity, and daily functioning after just a few treatments—even if they’ve tried multiple medications in the past without success.

Spravato represents a breakthrough approach in depression treatment, offering renewed hope for those who feel like nothing else has worked.